In a medium bowl, mix together the mayonnaise, ketchup, mustard, and pickle relish until they’re all nicely blended into a creamy mixture.

Next, sprinkle in the garlic powder, onion powder, salt, and pepper. Make sure to give it a good stir, ensuring even distribution of flavors.

Using a whisk or a spoon, mix until all ingredients are well combined and smooth.

Take a moment to taste your sauce. Feel free to adjust the seasoning with more salt or pepper if needed.

For best results, cover the bowl and refrigerate the sauce for at least 30 minutes.